📚 Syllabus & Course Curriculum
Biotechnology & Genetic Engineering
Module-by-module breakdown of Gene Drive Technology: Controlling Populations Through Genetic Engineering, from foundations to a certified capstone project.
Outline
Analyze the core biological principles underlying gene drive technology, including the mechanisms of gene editing and inheritance • Design genetic constructs for gene drive systems, considering factors such as gene expression, regulation, and targeting • Evaluate the potential applications and limitations of gene drive technology in controlling populations, including its potential impact on ecosystems and human health
Outline
Configure laboratory equipment and protocols for gene editing and gene drive experiments, including CRISPR-Cas9 and other gene editing tools • Develop and optimize protocols for gene drive construct assembly, transfection, and selection, using techniques such as PCR, sequencing, and microscopy • Collect and analyze data from gene drive experiments, including data on gene editing efficiency, off-target effects, and gene drive inheritance
Outline
Implement bioinformatics pipelines for gene drive data analysis, including tools such as BLAST, Bowtie, and SAMtools • Analyze gene drive sequencing data using computational tools such as Python, R, and MATLAB, including data visualization and statistical analysis • Develop and apply computational models to simulate gene drive dynamics and predict outcomes, using tools such as SLiM and msprime
Outline
Design and develop research proposals for gene drive projects, including hypothesis testing, experimental design, and sampling strategies • Evaluate and optimize experimental designs for gene drive research, including considerations of statistical power, sample size, and data quality • Develop and implement data management plans for gene drive research, including data storage, sharing, and preservation
Outline
Develop and apply advanced gene drive technologies, including technologies such as base editing and prime editing • Evaluate and optimize gene drive systems for specific applications, including disease control, conservation, and agriculture • Design and develop gene drive constructs for complex traits, including traits such as pesticide resistance and drought tolerance
Outline
Evaluate and comply with regulatory requirements for gene drive research, including regulations related to biosafety, biosecurity, and environmental release • Analyze and address bioethical concerns related to gene drive technology, including concerns related to equity, justice, and human rights • Develop and implement safety standards and protocols for gene drive research, including protocols for handling and containing gene drive organisms
Outline
Develop and evaluate business plans for gene drive products and services, including plans for intellectual property, marketing, and distribution • Analyze and pursue career pathways in gene drive research and development, including careers in academia, industry, and government • Evaluate and apply case studies of gene drive technology in various industries, including agriculture, biotechnology, and public health
Earn government-registered certification in Gene Drive Technology: Controlling Populations Through Genetic Engineering
e-Certificate and e-Marksheet issued on successful completion.
