Explore the genome-editing tools that came before โ and beside โ CRISPR.
Biotechnology & Genetic Engineering
Module-by-module breakdown of Zinc Finger Nucleases and TALENs: Alternatives to CRISPR, from foundations to a certified capstone project.
Outline
Analyze the structural and functional properties of zinc finger nucleases and TALENs โข Design and engineer zinc finger nucleases and TALENs for specific gene editing applications โข Evaluate the efficacy and specificity of zinc finger nucleases and TALENs in various cellular contexts
Outline
Configure and optimize laboratory protocols for the production and purification of zinc finger nucleases and TALENs โข Develop and implement efficient methods for the delivery and expression of zinc finger nucleases and TALENs in cells โข Collect and analyze data on the activity and specificity of zinc finger nucleases and TALENs using various biochemical and cellular assays
Outline
Implement computational tools and algorithms for the design and prediction of zinc finger nucleases and TALENs binding specificity โข Analyze and interpret large-scale genomic and transcriptomic data to identify potential targets for zinc finger nucleases and TALENs-mediated gene editing โข Develop and apply bioinformatics pipelines for the analysis and visualization of zinc finger nucleases and TALENs activity and specificity
Outline
Design and develop experimental strategies for the evaluation of zinc finger nucleases and TALENs efficacy and specificity โข Conduct and analyze experiments to assess the activity and specificity of zinc finger nucleases and TALENs in various cellular contexts โข Develop and implement robust methods for the validation and verification of zinc finger nucleases and TALENs-mediated gene editing outcomes
Outline
Develop and apply zinc finger nucleases and TALENs for the treatment of genetic diseases and complex disorders โข Design and engineer zinc finger nucleases and TALENs for the modification of stem cells and other cell types for regenerative medicine applications โข Evaluate the potential of zinc finger nucleases and TALENs for the development of novel therapies and treatments
Outline
Evaluate the regulatory frameworks and guidelines governing the use of zinc finger nucleases and TALENs in research and clinical applications โข Analyze and discuss the bioethical implications of zinc finger nucleases and TALENs technology and its potential impact on society โข Develop and implement strategies for ensuring compliance with safety standards and regulations in the handling and use of zinc finger nucleases and TALENs
Outline
Explore the current and future applications of zinc finger nucleases and TALENs in various industries, including biotechnology and pharmaceuticals โข Develop and evaluate business plans and strategies for the commercialization of zinc finger nucleases and TALENs technology โข Analyze and discuss case studies of successful applications of zinc finger nucleases and TALENs in research and industry
e-Certificate and e-Marksheet issued on successful completion.