📚 Syllabus & Course Curriculum
Data Science & Analytics
Module-by-module breakdown of Precision Oncology with Patient-Derived Organoids (PDOs), from foundations to a certified capstone project.
Establishment
• Tissue acquisition, consent and pathology coordination
• Digestion, matrix embedding and medium composition by tumour type
• Establishment rates and the selection bias in which tumours grow
Characterisation
• Histological and molecular comparison with the parent tumour
• Genomic drift across passages and its consequences
• Authentication and contamination control in an organoid biobank
Screening
• Assay formats, endpoints and viability readouts for 3D culture
• Dose-response fitting, AUC versus IC50 and their disagreement
• Plate effects, edge effects and normalisation controls
Correlation
• Published concordance between organoid response and clinical outcome
• Turnaround time against the clinical decision window
• Sensitivity and specificity of an organoid-guided recommendation
Translation
• Co-clinical trial designs and functional precision oncology studies
• Standardisation, quality control and accreditation requirements
• Cost, scalability and equitable access considerations
Earn government-registered certification in Precision Oncology with Patient-Derived Organoids (PDOs)
e-Certificate and e-Marksheet issued on successful completion.
