Analyse next-generation sequencing data end to end.
Data Science & Analytics
Module-by-module breakdown of Next-Generation Sequencing Data Analysis Course, from foundations to a certified capstone project.
Outline
Analyze the fundamental principles of molecular biology and genetics to understand the basis of next-generation sequencing technologies โข Evaluate the different types of next-generation sequencing platforms and their applications in various fields of research โข Design experimental approaches to generate high-quality sequencing data and troubleshoot common issues in sequencing workflows
Outline
Configure and optimize laboratory protocols for nucleic acid extraction, library preparation, and sequencing โข Develop and implement quality control measures to ensure the integrity and accuracy of sequencing data โข Operate and maintain sequencing instruments, including troubleshooting and resolving technical issues
Outline
Implement bioinformatics pipelines for data preprocessing, alignment, and variant calling using tools such as BWA and GATK โข Analyze and interpret sequencing data using statistical and computational methods, including machine learning and data visualization techniques โข Develop and apply custom scripts and workflows using programming languages such as Python and R to automate data analysis tasks
Outline
Design and develop research studies using next-generation sequencing technologies, including hypothesis testing and sample size calculation โข Evaluate and select appropriate sequencing strategies and protocols for specific research questions and applications โข Develop and implement data management plans to ensure the organization, storage, and sharing of sequencing data
Outline
Apply advanced bioinformatics tools and techniques, such as single-cell RNA sequencing and chromatin immunoprecipitation sequencing, to analyze and interpret complex sequencing data โข Develop and implement machine learning models to predict genomic features and identify patterns in sequencing data โข Integrate and analyze multi-omics data, including genomics, transcriptomics, and proteomics, to understand complex biological systems
Outline
Evaluate and apply regulatory guidelines and standards for the use of next-generation sequencing technologies in research and clinical settings โข Develop and implement bioethics and safety protocols for the handling and analysis of human subjects data and biological samples โข Configure and maintain laboratory safety equipment and procedures to ensure a safe working environment
Outline
Analyze and evaluate the applications of next-generation sequencing technologies in various industries, including biotechnology, pharmaceuticals, and healthcare โข Develop and implement career development plans and strategies for professionals in the field of next-generation sequencing โข Evaluate and discuss case studies of successful applications of next-generation sequencing technologies in research and industry settings
e-Certificate and e-Marksheet issued on successful completion.