📚 Syllabus & Course Curriculum
Drug Discovery & Pharmaceutical Sciences
Module-by-module breakdown of Hands-on In Silico ADMET Profiling, Drug-Likeness Screening and Toxicity Prediction for Lead Optimization, from foundations to a certified capstone project.
Outline
Understand the role of ADMET in drug discovery • Explore Lipinski’s Rule of Five and lead‑likeness concepts • Perform drug‑likeness evaluation with SwissADME • Retrieve structures and SMILES from PubChem
Outline
Analyse absorption, distribution, metabolism and excretion (ADME) parameters • Compare GI absorption, BBB permeation and solubility scores • Interpret CYP enzyme interactions and P‑glycoprotein substrate/inhibitor status • Generate comprehensive ADME profiles with pkCSM and ADMETlab
Outline
Predict acute toxicity, hepatotoxicity, mutagenicity and carcinogenicity with ProTox‑II • Assess hERG inhibition and cardiotoxicity risk • Interpret toxicity class and LD50 values • Combine docking scores with ADMET/toxicity data for holistic ranking
Earn government-registered certification in Hands-on In Silico ADMET Profiling, Drug-Likeness Screening and Toxicity Prediction for Lead Optimization
e-Certificate and e-Marksheet issued on successful completion.
