📚 Syllabus & Course Curriculum
Biotechnology & Genetic Engineering
Module-by-module breakdown of CRISPR based Gene Therapy, from foundations to a certified capstone project.
Outline
Trace the history and development of CRISPR technology from discovery to therapeutic application • Master the basic principles and mechanisms of CRISPR/Cas systems for targeted gene editing • Understand the fundamentals of gene therapy and its therapeutic potential • Learn the essential steps for employing CRISPR/Cas in clinical gene therapy protocols
Outline
Design effective guide RNAs and optimize CRISPR-Cas9 targeting strategies for precision editing • Execute hands-on CRISPR experiments with proper controls and validation methods • Analyze and interpret gene editing outcomes using sequencing and molecular assays
Outline
Compare viral and non-viral delivery systems for CRISPR components in therapeutic contexts • Evaluate lipid nanoparticles, AAV vectors, and electroporation techniques for in vivo delivery • Optimize delivery parameters to maximize editing efficiency while minimizing off-target effects
Outline
Explore landmark case studies of successful CRISPR-based gene therapies in clinical trials • Analyze challenges in therapeutic implementation and breakthrough solutions transforming the field • Investigate current applications across oncology, hematology, ophthalmology, and rare genetic disorders
Outline
Examine ethical implications and societal debates surrounding germline and somatic gene editing • Navigate current regulatory frameworks governing CRISPR-based gene therapies in India and globally • Understand approval processes, safety protocols, and compliance requirements for clinical translation
Outline
Design preclinical studies to evaluate efficacy, safety, and pharmacokinetics of gene therapies • Interpret clinical trial data and understand regulatory milestones for therapeutic approval • Assess manufacturing considerations and quality control for GMP-compliant production
Outline
Discover next-generation CRISPR systems including base editing, prime editing, and epigenome editing • Explore potential breakthrough applications in personalized medicine and regenerative therapies • Anticipate future challenges and opportunities in the evolving landscape of genetic medicine
Earn government-registered certification in CRISPR based Gene Therapy
e-Certificate and e-Marksheet issued on successful completion.
