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DSTC-01556 Online (e-LMS) Foundation

Bioinformatics Approach to Antimicrobial Resistance & HGT

by - Dr. Aishwarya Arun Andhare

A bioinformatics approach to antimicrobial resistance and gene transfer.

โ˜…โ˜…โ˜…โ˜…โ˜… Be the first to review โ€ข 3 Days ยท 4.5 hrs โ€ข e-Certificate Included
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From โ‚น2,500 + GST

๐Ÿ“š Syllabus & Course Curriculum

Antimicrobial Resistance (AMR)

Module-by-module breakdown of Bioinformatics Approach to Antimicrobial Resistance & HGT, from foundations to a certified capstone project.

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Isolates

โ€ข Illumina and Nanopore data, and why long reads resolve plasmids
โ€ข Assembly with SPAdes or Flye and assessing quality with QUAST and BUSCO
โ€ข Species confirmation and contamination screening before anything else

Resistome

โ€ข ResFinder, CARD-RGI and AMRFinderPlus and their different curation choices
โ€ข Acquired genes against chromosomal point mutations conferring resistance
โ€ข Genotype-to-phenotype concordance and where prediction reliably fails

Mobilome

โ€ข Plasmid reconstruction, replicon typing and MOB typing
โ€ข Integrons, transposons and insertion sequences flanking resistance genes
โ€ข Chromosomal against plasmid location and its epidemiological weight

Phylogeny

โ€ข MLST, cgMLST and core genome SNP analysis for relatedness
โ€ข Recombination masking before tree building with Gubbins
โ€ข Distinguishing clonal expansion from independent horizontal acquisition

Reporting

โ€ข Submission to public databases and the metadata standards expected
โ€ข Outbreak reporting and the SNP thresholds used, with their limits
โ€ข Writing a genomic AMR report that a microbiologist can act on

Earn government-registered certification in Bioinformatics Approach to Antimicrobial Resistance & HGT

e-Certificate and e-Marksheet issued on successful completion.

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Scholar Registration

For scholars whose department, college or employer pays the fee. We raise a proforma invoice to your institution; you attach the signed processing letter or bank slip.

The proforma invoice is emailed here as well as to you.
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