Master CAR-T cell therapy in oncology and beyond.
Immunology & Vaccine Development
Module-by-module breakdown of Advanced Course on CAR-T Therapy- Oncology and Beyond, from foundations to a certified capstone project.
Clinical Foundation
• Approved indications and the pivotal trial evidence behind each
• Patient selection, bridging therapy and lymphodepletion regimens
• Response assessment and durability in lymphoma, leukaemia and myeloma
Resistance
• Antigen loss and lineage switch as escape mechanisms
• T-cell exhaustion and failure of persistence
• Tumour microenvironment suppression of infused cells
Solid Tumours
• Trafficking, infiltration and physical barriers in solid tumours
• Antigen heterogeneity and on-target off-tumour toxicity risk
• Armoured CARs, cytokine support and combination strategies
Beyond Oncology
• CAR-T in autoimmune disease and the emerging clinical evidence
• CAR-Treg and CAR-NK approaches, and how they differ in risk profile
• Fibrosis, infection and senescence as investigational targets
Practice
• Toxicity management protocols and centre accreditation requirements
• Point-of-care manufacturing and decentralised models
• Cost, reimbursement and access in cost-constrained health systems
e-Certificate and e-Marksheet issued on successful completion.